Dries Mertens and Fernando Llorente scored late as holders Liverpool fell 2-0 at Napoli in the opening match of their Champions League title defence on Tuesday.
Mertens converted a penalty on 82 minutes and Llorente added a second in stoppage time as Napoli gained a measure of revenge for last season’s 1-0 defeat at Anfield that denied the Italians a spot in the knockout rounds.
The loss for Jurgen Klopp’s side makes them first reigning European champions to lose their opening game of the following campaign since AC Milan in 1994.
However Liverpool, who sit top of the Premier League after five straight wins, remain favourites alongside Napoli to progress from Group E despite Salzburg’s thrilling 6-2 win over Genk.
Liverpool also lost their group-stage match in Naples last season before going on to lift a sixth European Cup.
Llorente joined Napoli this season after playing his last game for former club Tottenham in the Champions League final defeat to Liverpool in Madrid in June.
He came on as a substitute and pounced on a rare Virgil van Dijk blunder after Mertens had opened the scoring from the spot to cause pandemonium among the crowd at the fiery Stadio San Paolo.
After two difficult opening matches in Serie A with seven goals conceded, Ancelotti’s side seem to have clicked into gear.
Napoli defenders Kalidou Kouilbaly and Mario Rui neutralised the threat of Egyptian star Mohamed Salah and Senegal’s Sadio Mane.